This is a great forum idea! For me, it depends on what you're doing exactly. If you have the specs, space, and equipment for bigger signs, welding and alumiunum are your best friend. Structurally, Steel is your friend. Outdoor signs; non rusting hardware is your friend. I like to do that, but if making smaller artwork, I like cutting aluminum and shaping it together without any welding or glue to hang in personal homes. I'll try to post an image if I can find one.
I also love using pvc for cleanliness and ease. But I believe its wasteful from an environmental standpoint. I like wood and recycled materials as well. I think every job entails a different approach.